Pract. ; This condition commonly affects adolescents and young adults and often occurs before 30 years of age. This site needs JavaScript to work properly. Different pattern of infection with involvement of the oral mucosa and capillitium. pp. Pityriasis alba typically resolves by itself within weeks to months. Hypopigmented lesions in PLC were noted mainly in younger ages, histopathologically they may show features of active or residual disease, beyond post-inflammatory hypopigmentation. 2009. pp. If the patient achieves clearing, it is worthwhile explaining that the intervals between outbreaks will be very important to monitor, as everyone has a different rhythm. However, to the best of our knowledge, no studies describing histopathological findings in these lesions are reported in literature. Exocytosis was seen in 45.1% of the cases. The lesions can appear singly or in groups, and can coalesce into large areas of rash. Typically there is a patchy lichenoid infiltrate that is very focal with overlying parakeratosis. J. Dermatol. Hypopigmented lesions were present on the face in 12 (57.14%) patients. When this form of parapsoriasis was being described in the literature it was grouped under the "rhythmic. If the suspicion of mycosis fungoides is pursued the next surprising finding is that there often is T-cell clonality by molecular studies. Bookshelf The second stage is a moderate grade and people will have larger areas of areas on their body that will be mostly covered in pale, tan, or pinkish-red dots that also itches. A cross-sectional observational study included twenty-one patients with PLC recruited in a period of twelve months. Pityriasis lichenoides chronica was diagnosed in 39 cases (76.47%) and pityriasis lichenoides et varioliformis acuta (PLEVA) in 12 cases (23.53%). Subsequent development of inflammatory arthritis, however, necessitated discontinuation of pembrolizumab and initiation of methotrexate therapy. (This review includes data from the pediatric registry of cutaneous lymphomas. There are several theories about the cause of the disease, including that it may be a response by the immune system to an infection or medication. Treatment may include: 1. There are systemic symptoms as well, which can include high fever, abdominal pain, diarrhea, joint pain, breathing difficulties, and changes in mental status. Dermatol. 2007. pp. Introduction. Keratosis lichenoides chronica is rare, with only around 70 cases reported in the medical literature as of 2019 [1]. Pityriasis lichenoides chronica (PLC) PLC has a more low-grade clinical course than PLEVA. PLC is the most common form and presents with small red-brown papules with an adherent 'mica-like' scale. Br J Dermatol. The following differential diagnosis may be considered: A. Pityriasis rosea B. Psoriasis C. Pityriasis lichenoides Chronica D. Small plaque parapsoriasis E. All of the above . Pityriasis lichenoides chronica: stratification by molecular and phenotypic profile. There have been several cases reported of mycosis fungoides appearing in patients who exhibited PLC. Youssef R, Abdel-Halim MRE, Abdel Halim DM, Fawzy MM, Hussein MF, Elmasry MF, Sayed SS, Abo Eid NM. Federal government websites often end in .gov or .mil. NORD is a registered 501(c)(3) charity organization. Joshi R. Stratum corneum findings as clues to histological diagnosis of pityriasis lichenoides chronica. Unable to load your collection due to an error, Unable to load your delegates due to an error. It is not contagious. Pityriasis lichenoides has distinct acute and chronic forms, which are usually distinct entities; however, lesions may evolve from the acute to chronic type. Accessibility The acute form, pityriasis lichenoides et varioliformis acuta (PLEVA), and the chronic form, pityriasis lichenoides chronica (PLC), sit at either end of a disease spectrum with many patients showing overlapping features. Pityriasis lichenoides represents a group of uncommon skin disorders that tend to affect children and young adults, and are divided into two main conditions: pityriasis lichenoides chronica (PLC) and pityriasis lichenoides et varioliformis acuta (PLEVA). Bethesda, MD 20894, Web Policies Il s'agit d'un test ouvert, un seul bras, international, multicentrique tendu plusieurs patients Programme d'accs (MPEAP). On the back a Christmas tree like configuration can also arise from parallel oval lesions draping down and away from the spine (the tree trunk). Patients with FUMHD require hospitalization. Arch Dermatol Res. 2019 Nov;311(9):673-678. doi: 10.1007/s00403-019-01949-2. Symptoms. The lesions of PLC show a monotonous morphology of roughly the same-sized lesions on a given patient as shown here on the thigh. Pityriasis Lichenoides Chronica. HHS Vulnerability Disclosure, Help Continuing Medical Education (CME/CE) Courses. Pityriasis lichenoides chronica, PLEVA, and lymphomatoid papulosis share several clinical and immunohistologic features, suggesting that these disorders are interrelated and part of a spectrum of clonal T-cell cutaneous lymphoproliferative disorders. There are two types of pityriasis lichenoides: an acute form usually found in children known as pityriasis lichenoides et varioliformis acuta (PLEVA), and a more long-lasting form known as pityriasis lichenoides chronica (PLC). Venereol. If left untreated, pityriasis lichenoides chronica can lead to complications, such as a secondary bacterial infection. With the lichenoid inflammation there is often post inflammatory hyperpigmentation in skin of color. However, there are two eruptions that can mimic PLC and to some degree overlap with it. If you need help finding information about a disease, please Contact Us. Want to view more content from Cancer Therapy Advisor? The etiology of PLEVA remains unknown. Youve read {{metering-count}} of {{metering-total}} articles this month. Pityriasis lichenoides (PL) is a papulosquamous disorder often considered a form of reactive dermatosis and classified with small plaque parapsoriasis (digitate dermatosis). Pityriasis lichenoides et varioliformis acuta and pityriasis lichenoides chronica: comparison of lesional T-cell subsets and investigation of viral associations. 2015 Mar-Apr;86(2):121-5. doi: 10.1016/j.rchipe.2015.04.024. Pityriasis lichenoides chronica (PLC) is rarely as symptomatic as it is alarming. The differential diagnosis includes guttate psoriasis, pityriasis versicolor, papular pityriasis rosea . It typically does not scar. 2007. pp. Patients must rely on the personal and individualized medical advice of their qualified health care professionals before seeking any information related to their particular diagnosis, cure or treatment of a condition or disorder. Topical corticosteroids such as hydrocortisone, which can help reduce itching and inflammation; 2. PUVA-induced pityriasis lichenoides chronica-like papular lesions in patients with mycosis fungoides: a clinical, histopathological and immunohistochemical study. Br. The most surprising finding on biopsy is that if the pathologist is not aware of this being a monomorphous eruption of small papules, the pathology may be interpreted as being suspicious of mycosis fungoides. In that setting, the clinical and pathological features of PLC would be interpreted as a form of chronic graft-versus-host disease. Register now at no charge to access unlimited clinical news, full-length features, case studies, conference coverage, and more. Pityriasis lichenoides affects roughly 1 in 2000 people per year. Disclaimer, National Library of Medicine Who is at Risk for Developing this Disease? ), Ersoy-Evans, S, Hapa, AA, Boztepe, G, Sahin, S, Klemen, F. Narrowband ultraviolet-B phototherapy in pityriasis lichenoides chronica. [Mycosis fungoides in children and adolescents: a report of six cases with predominantly hypopigmentation, along with a literature review]. Epub 2019 Jul 12. Discussion. Skin Diseases. 2007; 38: 479-90. [from NCI] Term Hierarchy GTR MeSH [2350][2228] Diagnosis of PLC is based on a doctor observing papules on the skin. PMC Thus, a history of a rhythmic eruption that fades is a key finding in the history. Pityriasis lichenoides: pathophysiology, classification, and treatment. Pityriasis lichenoides chronica in black patients. ), (The classic paper that put antibiotic therapy at the forefront of pityriasis lichenoides management. Initially a small pink papule occurs that turns a reddish-brown colour Usually a fine mica-like adherent scale attached to . This review provides a broad view of the clinical spectrum in the pediatric population. Call +91 8080 850 950 to book an appointment or to consult and order online. Pityriasis lichenoides chronica: stratification by molecular and phenotypic profile. "Pityriasis lichenoides in children: therapeutic response to erythromycin". To make the diagnosis of pityriasis lichenoides, a dermatologist will biopsy a lesion to look for the characteristic pattern of inflammation in the skin. Concept. Pityriasis lichenoides in childhood: a retrospective review of 124 patients. 10/13/2022Fall 2022 Newsletter Is Available, 7/19/20222022 Fall Conference Newsletter Is Available, 7/5/2022Summer 2022 Newsletter Is Available, 4/4/2022Spring 2022 Newsletter Is Available, 12/21/2021Winter 2021 Newsletter Is Available, 12/7/2021AOCD Board of Trustees Pens Letter to ABD Regarding Certification Recognition, 10/19/2021Fall 2021 Newsletter Is Available, 9/16/2021AOCD Thursday Bulletin for September 16, 2021, 8/12/2021AOCD Thursday Bulletin for August 12, 2021, 7/22/2021AOCD Thursday Bulletin for July 22, 2021, 7/15/2021AOCD Thursday Bulletin for July 15, 2021, 7/8/2021AOCD Thursday Bulletin for July 8, 2021, 2/23/2023 2/26/2023AOCD 2023 Spring New Trends in Dermatology, 4/9/2024 4/15/2024AOCD 2024 Spring New Trends in Dermatology, 2/17/2025 2/23/2025AOCD 2025 Spring New Trends in Dermatology, 2902 North Baltimore Street | P.O. Intravenous corticosteroids such as methylprednisolone may be used to treat more severe or widespread pityriasis lichenoides. One unique feature of PLC is that once controlled with methotrexate the dose can often be reduced to 5mg per week to suppress new crops from appearing. Pityriasis lichenoides in children: therapeutic response to erythromycin. vol. MeSH 441-5. The lesions then evolve, developing small blisters and pustules, and eventually ulcerate and crust over. pp. It proliferates in "Dandruff ' and 'Seborrhoeic Dermatitis' and in the diseases/ conditions discussed herein - prefixed Pityriasis. Histopathologic analysis is useful in diagnosis, and dermoscopic findings have been described in several small case series. All rights reserved. Genetic and Rare Diseases Information Center (GARD). Methods: Tetracycline and its derivatives have also been used at the same doses used for acne; however, given the tendency to utilize phototherapy and for the eruption to appear in children, these antibiotics tend to be prescribed less often. Pityriasis lichenoides is an uncommon disease of the skin that can present in three different forms: pityriasis lichenoides et varioliformis acuta (PLEVA), pityriasis lichenoides chronica (PLC), and febrile ulceronecrotic Mucha-Habermann disease (FUMHD). In the PLC vesicles were mostly missing! Skin biopsy is helpful in establishing the diagnosis. The papules develop gradually. Pityriasis lichenoides (PL) is an uncommon cutaneous rash of uncertain aetiology . Clipboard, Search History, and several other advanced features are temporarily unavailable. J Am Acad Dermatol. A skin biopsy from hypopigmented lesions whenever present was taken and assessed with routine haematoxylin and eosin stain. These three forms represent a spectrum of disease presentation. The term "pityriasis lichenoides" is frequently used to refer to the spectrum of these disorders. (Pityriasis lichenoides chronica is one of the most common forms of parapsoriasis in children. We would like to hear your feedback as we continue to refine this new version of the GARD website. Besides these inherent obstacles, PL merits awareness because of its potential to progress to cutaneous lymphoma or an ulceronecrotic presentation, both of which carry a . Because of the rare but possible transformation to malignancy, careful follow-up and repeated biopsies is advised in chronic intermittent disease. This observation is useful in trying to answer the PLC patients question about what causes this? Please read. Because it is rare, the eruption is very difficult to diagnose, and the patient may go from doctor to doctor looking for the diagnosis. official website and that any information you provide is encrypted However, severe cases of this condition are difficult to treat. Her second book, Music, Music, You Can Too!, a nonfiction children's book, was released in July 2020. Pityriasis lichenoides chronica (PLC) is a skin disease that causes the development of small, scaling, raised spots ( papules) on the skin. PLEVA and PLC are thought to lie on a disease spectrum, with PLEVA being more acute and symptomatic and PLC being more chronic in nature, but some patients may show features of both . PLC is the relatively mild form of the disease pityriasis lichenoides. There is a proliferation of immune cells, called T-cells, in the skin. Pityriasis lichenoides chronica (PLC) is rarely as symptomatic as it is alarming. ), (Pityriasis lichenoides chronica is one of the most common forms of parapsoriasis in children. The most reliable systemic therapy for PLC is weekly methotrexate at doses similar to those successful for psoriasis. Peeling of the skin is often observed, after the rash resolves, noticeable scars may remain. The medical information provided in this site is for educational purposes only and is the property of the American Osteopathic College of Dermatology. The aim of this study is to evaluate the hypopigmented lesions encountered in PLC patients and to shed light on their histopathological features. (With the declining use of photochemotherapy, narrowband has become the most available office-based phototherapy for pityriasis lichenoides. 1979 Mar;100(3):297-302. doi: 10.1111/j.1365-2133.1979.tb06202.x. As the treatment outcome may vary from person to person, visit one of our clinics or chat online for a detailed assessment with our specialists. Also, the treatment of children is slightly different from that of adults, with an emphasis on antibiotics. Varicella: Clinical morphology can be very similar. If it does leave a brown mark it can take several months before they start to fade away. Again, the benign nature of the disease must balance any risk of hepatotoxicity or bone marrow suppression. The more acute (sudden onset) form is known as pityriasis lichenoides et varioliformis acuta ( PLEVA ), also known as Mucha-Habermann disease . Pityriasis lichenoides chronica - About the Disease - Genetic and Rare Diseases Information Center Thank you for visiting the new GARD website. The clinical features, diagnosis, and management of . Oral or intravenous corticosteroids may be of benefit. Khachemoune, A, Blyumin, ML. Some people also develop superficial sores or ulcers. The cause is unclear but it appears to be an autoimmune disease (an immune system malfunction). In most cases, Pityriasis lichenoides chronica is not serious. The major factor complicating any efficacy assessment is the remitting nature of the disease. It is hypothesized that PLC is caused by a dermal hypersensitivity reaction to an infectious agent such as the virus Epstein Barr Virus (EBV). Due to the history of recurrence with this disease, combination therapy is recommended with a gradual taper of all modalities. Pityriasis lichenoides chronica (PLC) lesions are reported to subside with post-inflammatory hypopigmentation (PIH); hence, the most widely perceived nature of hypopigmented macules in PLC is PIH. Treatment of Pityriasis Lichenoides Chronica with custom-made Homeopathy medicines can help you cure Pityriasis Lichenoides Chronica naturally. Pityriasis lichenoides has been seen in association with many illnesses, including streptococcus, HIV, chickenpox, Epstein-Barr virus, cytomegalovirus, and hepatitis C. Some medications, such as antihistamines, estrogen-progesterone therapy, and the measles vaccine, have been implicated in pityriasis lichenoides. ), (With the declining use of photochemotherapy, narrowband has become the most available office-based phototherapy for pityriasis lichenoides. PLC lesions may appear over the course of several days, weeks or months. It can occur in people of any race, age, or sex. vol. The chronica implies that I will have spotted skin (seasonally reddish or white) as long as I am alive. Skin lightens and lesions fade gradually, but in severe cases, lesions may recur or persist beyond a year. Oral steroids are sometimes used with the antibiotics to speed clearance of lesions. PLC is more common and has a more mild presentation compared with PLEVA. Call +91 8080 850 950 to book an appointment or to consult and order online. Pityriasis lichenoides (PL) is a skin condition of unclear etiology that occurs not uncommonly in childhood. Cutis. FUMHD is treated in hospital with medications including IV gamma globulin, dapsone, cyclosporine, and methotrexate. A prolonged course of antibiotics, such as erythromycin or, Roger C. Byrd, DO Clinical Manuscript Competition, Dermatopathology of Summer Skin Conditions, Update on Eczema: Focus on Atopic Dermatitis, 2022 Fall Conference Newsletter Is Available, AOCD Board of Trustees Pens Letter to ABD Regarding Certification Recognition, AOCD Thursday Bulletin for September 16, 2021, AOCD Thursday Bulletin for August 12, 2021, AOCD 2023 Spring New Trends in Dermatology, AOCD 2024 Spring New Trends in Dermatology, AOCD 2025 Spring New Trends in Dermatology. We want you to take advantage of everything Cancer Therapy Advisor has to offer. I am 35 years old now and preganant. What are the symptoms of pityriasis lichenoides chronica? To view unlimited content, log in or register for free. If you have a specific question or concern about a skin lesion or disease, please consult a dermatologist. The majority of cases have been described in adults aged 20-40 years; 24% of cases were children [2]. We present a case of a mid-20s female who was diagnosed with PLEVA based on clinical and . Fifty-one patients with pityriasis lichenoides (not subdivided into PLEVA and PLC) were . Histopathologically, basal cell vacuolation and perivascular infiltrate were seen in all the cases. An official website of the United States government. A person with PLC tends to have multiple episodes of papules on the skin lasting for months or a few years, meaning the disease is chronic. The rash can come and go, lasting for 1.5 to 18 months without treatment. 3, 4 Traditionally, two clinical forms are described: pityriasis lichenoides et varioliformis acuta (PLEVA) and pityriasis lichenoides chronica (PLC). But in the wild-type form of the disease, we can only speculate it is a similar relapsing/remitting misguided inflammatory response. [2350], The cause of PLC is unknown, but it is not contagious. As a published author, I thought my third book might center around living with PLC (or pityriasis lichenoides chronica) a diagnosis I received in my teens and have lived with ever since. The relevance of recognizing clinical and morphologic features of pityriasis lichenoides: clinicopathological study of 29 cases. The .gov means its official. This information is provided by the National Institutes of Health (NIH) hypopigmented; pityriasis lichenoides chronica; post-inflammatory hypopigmentation. (In this review, the histologic features that characterize PLC and differentiate it from the acute form are reviewed. NORD is not a medical provider or health care facility and thus can neither diagnose any disease or disorder nor endorse or recommend any specific medical treatments. Calcineurin inhibitors such as tacrolimus ointment may be used in addition to a topical corticosteroid to help stop the skin from becoming more red and inflamed; 3. This safest therapy touted for PLC is also the least reliable, but worth pursuing due to the benign nature of the drugs: antibiotics at acne doses and durations. ), Truhan, AP, Hebert, AA, Esterly, NB. While patients can often be cleared, the real benefit is in prolongation of intervals between the courses of phototherapy. Diagnosis of pityriasis lichenoides may be difficult due to a wide spectrum of clinical presentations. Hum. One is the more virulent and scarring rhythmic eruption of lymphomatoid papulosis. ), Lynch, PJ, Saied, NK. It is in fact a milder but chronic variant of the acute form. Within this spectrum, cases may be classified as pityriasis lichenoides et varioliformis acuta (PLEVA), the acute form, or pityriasis lichenoides chronica (PLC), the chronic form. 109-13. One characteristic place to see a string-of -beadslike configuration of these lesions is around the axilla or inguinal region. Careers. PLEVA and PLC will both eventually resolve without treatment, but it can take months or years. The compact, covering, centrally adherent cover scales of Pityriasis lichenoides chronica are always missing. Pityriasis lichenoides is a self-limiting papular, clonal T-cell disorder that exists on a disease spectrum. Pityriasis lichenoides chronica, also called pityriasis lichenoides et varioliformis acuta, is a rare skin disorder that most commonly affects young children and adolescents. It is seen slightly more often in males and in late childhood to early adulthood. Pityriasis lichenoides - About the Disease - Genetic and Rare Diseases Information Center National Center for Advancing Translational Sciences We recently launched the new GARD website and are still developing specific pages. Given the lack of symptoms, many patients tend to ignore it and given the diseases natural history of spontaneous involution their wishes tend to be fulfilledit goes away. Consult our specialists today for a detailed evaluation and to start your customised Homeopathy treatment of Pityriasis Lichenoides Chronica. In the setting of a transplant, we know the cause. Our mission is to provide practice-focused clinical and drug information that is reflective of current and emerging principles of care that will help to inform oncology decisions. Learn more. Yes, Pityriasis lichenoides chronica is a skin disorder that normally resolves on its own, but treatment with medications may speed up the process. A prolonged course of antibiotics, such as erythromycin or tetracycline, is often given to decrease the duration of the disease. Pityriasis rosea typically begins with an oval, slightly raised, scaly patch called the herald patch on the face, back, chest or abdomen. Box 7525 | Kirksville, Missouri 63501. It is characterized by small, slightly raised pink spots that tend to come together in groups. Treatment options may include antibiotics, creams for the skin, or phototherapy. Pityriasis lichenoides chronica or pityriasis lichenoides et varioliformis acuta (PLEVA) are associated with infections, including Toxoplasma gondii, Epstein-Barr virus, parvovirus B16, HIV, Group A streptococci, staphylococci and others. Clayton R, Warin A. Pityriasis lichenoides chronica presenting as hypopigmentation. Before the herald patch appears, some people have headache, fatigue, fever or sore throat. This is probably the most commonly used approach, since many patients do this at home before and after seeing a dermatologist. Before these lesions appear, people may experience fever, chills, fatigue, and joint pain. (Weekly methotrexate has become a reliable modality for controlling pityriasis lichenoides when symptoms and signs disrupt the patients quality of life.). The lesions may also appear on other parts of the body. In severe cases, medications that suppress the immune system response (immunosuppressants) may be used.[2350][2228]. The AOCD limits permission for downloading education material for personal use only. One of the leading etiological hypotheses is that pityriasis lichenoides is a form of atypical immune response in individuals genetically susceptible to a foreign agent (s). However, some patients with PL have developed large plaque parapsoriasis (LPP) and mycosis fungoides (MF), and lymphoid atypia and T-cell clonality have been reported in . Because of the rare but possible transformation to malignancy, careful follow-up and repeated biopsies is advised in chronic intermittent disease. 29-36. The macrolides erythromycin, azithromycin, and clarithromycin at doses of 250mg to 500mg per day for at least 2 months have been the most popular. Pityriasis Lichenoides Chronica (PLC) is a skin condition of unknown cause that affects young adults and adolescents. Information on Clinical Trials and Research Studies, 5 Myths About Orphan Drugs and the Orphan Drug Act, NIH GARD Report: Pityriasis lichenoides chronica. The disease can occur in people of all ages and races. Pityriasis lichenoides chronica isnt a disease that anyone should be ashamed of, and it can happen to anyone. While patients can often be cleared, the real benefit is in prolongation of intervals between the courses of phototherapy. In addition, the lesions tend to disappear with sunlight exposure, so the face and repetitively sun-drenched areas of the skin tend to escape the rhythmic eruption while truncal and proximal extremity lesions dominate. Gelmetti C, Rigoni C, Alessi E et al. The first stage is the mildest grade and it is characterized by a few small, generalized patches of skin that may itch. Markus JR, Carvalho VO, Lima MN et al. The https:// ensures that you are connecting to the Rizzo FA, Vilar EG, Pantaleo L, Fonseca EC, Magrin PF, Henrique-Xavier M, Rochael MC. Pityriasis lichenoides (Pityriasis lichenoides et varioliformis acuta, Pityriasis lichenoides chronica) Lymphomatoid papulosis; Small plaque parapsoriasis (Digitate dermatosis, Xanthoerythrodermia perstans) Large plaque parapsoriasis (Retiform parapsoriasis) The acute form typically appears in children and young adults, with crops of asymptomatic chickenpox-like lesions that typically resolve, often with scarring, within weeks to months. There is not enough of an association to warrant serologic studies or antiviral therapy. Lesions of PLEVA may be associated with burning and pruritus.. A person with PLC tends to have multiple episodes of papules on the skin lasting for months or a few years, meaning the disease is chronic. Before PLEVA can look very similar to some types of cutaneous lymphoma, so it is very important to exclude malignant or premalignant conditions during the diagnosis. Le programme est . It progresses through three stages: Stage I: pale red patches, which may itch; Stage II: light brown patches with a lighter border; and Stage III: dark brown patches with indistinct borders. FOIA There can be mild itching or burning, but usually no other symptoms are present in PLEVA. pityriasis lichenoides chronica: an eruption, lasting up to a few years, of reddish-brown papules with central scaling; it clears without scarring. Histopathologically, hypopigmented lesions showed features of post-inflammatory hypopigmentation in 19% of patients, residual PLC in 52.4% and active PLC 28.6% of patients. Consult our specialists today for a detailed evaluation and to start your customised Homeopathy medicines for Pityriasis Lichenoides Chronica. Some people also develop superficial sores or ulcers. In order of ease of administration and patient acceptability it is not unusual to utilize phototherapy to clear up old lesions and inhibit the development of new ones for a given period of time. The papules develop scales and the skin is rendered flaky In general, pityriasis lichenoides may be acute or chronic. [1] A variety of infectious pathogens have been linked to this disease, including HIV, varicella-zoster virus . A diary of some type would suffice. There are two types of pityriasis lichenoides: an acute (more sudden onset and less persistent) form known as pityriasis lichenoides et varioliformis acuta (PLEVA), and a milder, more persistent form known as pityriasis lichenoides chronica (PLC). Chronic form of pityriasis lichenoides It can show up as papules that are dome-shaped, reddened, and elevated lesions. There is no cure for pityriasis lichenoides. Pityriasis lichenoides (PL) is an uncommon, acquired spectrum of skin conditions that poses various challenges to patients as well as clinicians. 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